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Postdoctoral position, Medieval Pathogen Palaeogenomics

KU - SCIENCE - NBI

Oprettet:
16-05-2019
Udløber:
02-06-2019

Section for Evolutionary Genomics, Biological Institute, Faculty of Science, University of Copenhagen


The Section for Evolutionary Genomics is looking for a skilled scientist to fill a ca 3-year position (38 months), as part of a recently funded project that will investigate the history of human pathogens in the city of Trondheim, Norway. This project is funded by the Carlsberg Foundation as part of a larger grant to study the genetic history of northern Europe, using genomic DNA extracted and sequenced from skeletal samples. This postdoctoral position will be tasked with mining the generated shotgun genomic DNA for pathogen sequences, with the aim of recovering complete ancient pathogen genomes. Recovered genomes will then be analysed in the broader evolutionary context to provide enhanced insights into questions such as: which pathogens were present at what times, and how do they relate to other ancient and modern pathogen diversity. Therefore, critical skills required include: prior experience in the extraction of ancient DNA and generation of sequencing libraries on said DNA, as well as the application of target enrichment methodologies such as hybridization capture. Additionally, the candidate will be expected to have a very sound background in the computational approaches linked to analysing such ancient data, as well as prior familiarity with human pathogen genetics and biology. The position would be supervised by Prof. Tom Gilbert.

Main tasks

  • Computationally screen shotgun palaeogenomic data to identify pathogens
  • Where needed generate extra data to supplement findings, including through the use of target-capture enrichment
  • Analyse recovered data in the broader historical and phylogenetic / evolutionary genomic context
  • Prepare manuscripts for publication
Mandatory Qualifications
  • Relevant scientific background – at least PhD level with thesis or prior postdoc working on ancient DNA
  • Prior experience in the extraction of nucleic acids from historic/ancient samples including bone and tooth samples
  • Prior experience in the generation of Illumina based shotgun sequencing libraries on ancient DNA
  • Prior experience using computational metagenomic methods to analyse such data
  • Highly organized, and able to work both as part of a team but also under their own initiative.
  • Excellent teamwork and communication skills, both verbal and written
  • Fluency in English (written, reading, spoken)
  • Have a good publication record, with at least one first-author publication
Other Qualifications of Considerable Interest
  • Knowledge of the history of Northern Europe over the past millennium, in the context of humans and their pathogens.
  • Knowledge of a Scandinavian language
Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/. Inquiries about the position can be made to Prof Tom Gilbert (tgilbert@snm.ku.dk)

The position will start as soon after 1st August 2019 as possible.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Terms of employment
The position is covered by the Memorandum on Job Structure for Academic Staff.
Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.
The starting salary is currently up to DKK 430.569 including annual supplement (+ pension up to DKK 73.627). Negotiation for salary supplement is possible.
The application, in English, must be submitted electronically by clicking APPLY NOW below.


Please include
  • Curriculum vita, including clear documentation of above listed mandatory skills requirement.
  • Diplomas (Master and PhD degree or equivalent)
  • Complete publication list
The deadline for applications is 3 June 2019, 23:59 GMT +1.

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

Praktisk information
Oprettet:
16-05-2019
Udløber:
02-06-2019
Kviknummer:
LJA-73434796
Jobtype:
Fuldtid
Arbejdsområder:
Forskning og udvikling,
Salg
Beliggenhed