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A 3-year Post.Doc. position is available in the subject of immunotherapy of glioblastoma, Department of Clinical Medicine, Aarhus University, Denmark 1023951

Aarhus Universitet


Post. Doc. fellowship: Guided immunotherapy of glioblastoma by combined targeting of innate and adaptive immune checkpoints.

The project is focused on new agents of immunotherapy towards glioblastoma by using in vivo CRISPR model The project is led by associate professor Martin K. Thomsen, at Department of Clinical Medicine, Aarhus University, Denmark and is funded by The Danish Ministry of Health.

The project will focus on targeting glioblastoma by innate and adaptive immune checkpoints in an in vivo CRISPR-based model. The in vivo model is generated by CRISPR/Cas9 technology delivered with AAV to induce glioblastoma tumours containing different key gene mutations, all known from human cancer. The effect of the tested immunotherapies will be followed by MRi and PET scanning during disease progression and treatment. Evaluation of the treatment by tumour regression and molecular analysis including single-cell sequencing will lead to insight to the mechanism. Also, generation of genetic engineered T-cells for infusion to tumour baring mice will validate the mechanism.

The preferred candidate must have a strong interest in cancer biology and a desire to work with in vivo models. Furthermore, the techniques related to the project are broad, ranging from CRISPR/Cas9 and cloning, to bioinformatics and central methods in immunology and immunotherapy. The ideal candidate is highly skilled with good learning skills and a positive mind-set as it is expected that the applicant is leading all parts of the project. Therefore, a profound interest in both the methodological and the biological/medical aspects of the project is a selection criteria. During the Post.Doc. it is expected that part of the project is carried out together with collaborators.

The candidate must have a relevant Ph.D. degree and first author publications in well-established journals. Experience with mouse handling, immunology and cell culture work are an advantage.
Expected starting date will be April 1st, 2019 or earlier.

Further information regarding the fellowship can be obtained by contacting Martin K. Thomsen at

Applications must contain the applicants CV, motivation letter, list of publications, name, address and at least one letter of support. Applications must be received no later than 17th February 2019 and interviews will be held during the advertisement period and in February.

Required qualifications
Appointment as a postdoc requires academic qualifications at PhD level.

Formalities and references

  • Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities (
  • The appointment is in accordance with the Danish Confederation of Professional Associations ( (Akademikerne).
  • Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health (
  • Further information on qualification requirements and job description can be found in the Memorandum on Job Structure for Academic Staff at Danish Universities ( (in Danish).

Applications must be accompanied by a CV, diploma, a list of publications as well as a teaching portfolio. Template for applicant - postdoc ( must be completed and uploaded under Other information to consider. A maximum of five of the publications of greatest relevance to the job must be submitted.

Further information on the application and supplementary materials may be found in the facultys Guidelines for applicants for academic positions ( and Aarhus Universitys Guidelines on the use of teaching portfolios (

The assessment committee may decide to include non-submitted material in its assessment. In such cases, the applicant will be informed and obliged to submit material, unless the application is withdrawn.

Applications submitted through channels other than the online application form below or applications which are not received by the application deadline will not be considered.

All interested candidates are encouraged to apply, regardless of their personal background.

All applications must be made online and received by: 17.02.2019

International applicant?
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here ( Aarhus University also has a Junior Researcher Development Programme. You can read more about it here (


Praktisk information
Forskning og udvikling
Lignende job
Arkitektskolen Aarhus
Arkitektskolen Aarhus
Erhvervsakademi Dania (Arvikavej 2A, Skive)